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Photoaffinity labeling of PKC isozymes by phorbol ester derivatives.

K Uotsu, M Sodeoka, M Shibasaki
Bioorganic & Medicinal Chemistry 1998 July
Photoaffinity probes PPDA and PPTD, which have diazoacetyl and trifluorodiazopropionyl group at C-13 position in phorbol, respectively, were synthesized. Photoaffinity labeling of protein kinase C isozymes by both the probes resulted in specific cross-linking.

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