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What's new in the treatment of cutaneous melanoma?

As surveyors of the skin, it is important for dermatologists to be aware of recent developments in the management of melanoma. Revised recommendations for surgical margins will be reviewed as will the use of Mohs micrographic surgery for the excision of melanoma, in particular lentigo maligna. An explanation of the technique of sentinel node biopsy is followed by a discussion of the results of recent clinical trials. Adjuvant immunotherapy in the form of vaccines and high-dose alpha-interferon is outlined as is the concept of biochemotherapy for more advanced disease.

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Group 7SearchHeart failure treatmentPapersTopicsCollectionsEffects of Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Patients With Heart Failure Importance: Only 1 class of glucose-lowering agents-sodium-glucose cotransporter 2 (SGLT2) inhibitors-has been reported to decrease the risk of cardiovascular events primarily by reducingSeptember 1, 2017: JAMA CardiologyAssociations of albuminuria in patients with chronic heart failure: findings in the ALiskiren Observation of heart Failure Treatment study.CONCLUSIONS: Increased UACR is common in patients with heart failure, including non-diabetics. Urinary albumin creatininineJul, 2011: European Journal of Heart FailureRandomized Controlled TrialEffects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.Review

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