[Helical x-ray computed tomography of renal arteries. Apropos of 300 patients].

PURPOSE: To evaluate the role of helical CT angiography (CTA) in the detection of renal artery stenosis in hypertensive patients.

MATERIALS AND METHODS: We studied 300 hypertensive patients (50 prospectively and 250 consecutively) with CTA and arteriography (n = 118). Helical acquisition (collimation 3 mm; pitch = 1, 20 seconds acquisition time) was performed 20-45 seconds after contrast injection (300 mgl/ml; 120 ml, 4 ml/sec). Transverse axial views and 3D reconstructions were analyzed (360 degrees interpolation algorithm, 1 mm overlapped).

RESULTS: In the prospective series, CTA sensitivity was 100% for main renal artery stenoses and specificity was 98.2%; however 7/32 renal accessory arteries were not visualized. In the 300 patients studied, seventy-four stenoses were detected. There were 5 false-positive and 5 false-negative studies. Secondary hypertension was detected in 26% of patients (including 14 cases of adrenal hyperplasia).

CONCLUSION: CTA is a promising technique for the detection of renal artery stenosis in hypertensive patients.