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CASE REPORTS
JOURNAL ARTICLE
Multiorgan dysfunction and disseminated intravascular coagulation in children receiving lamotrigine and valproic acid.
Neurology 1997 November
Two children developed multiorgan dysfunction with disseminated intravascular coagulation 9 days after lamotrigine was added to their antiepileptic therapy, which included valproic acid. During the episodes, rhabdomyolysis was detected in one of them, while being seizure-free, suggesting that this adverse reaction may involve muscular tissue.
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