[Primary antiphospholipid antibody syndrome in pregnancy--successful pregnancy outcome after intravenous immunoglobulin administration].

Primary antiphospholipid antibody syndrome is characterized by intrauterine fetal death and arterial and/or venous thrombosis. The clinical course of a 37-year-old pregnant woman with a history of eight previous miscarriages is presented. By application of intravenous immunoglobulin (Venimmun Behringwerke Marburg/Lahn) a successful pregnancy could be accomplished. Diagnosis, immunologic pathomechanisms, possible treatment modalities as well as the obstetric management of this autoimmune disease will be discussed.