We have located links that may give you full text access.
Journal Article
Review
[Pituitary adenoma: mechanisms of endocrine oncogenesis].
La Revue du Praticien 1996 June 16
Molecular studies on pituitary adenomas support a major role of molecular alterations in the pathogenesis of pituitary adenomas. Nevertheless, alterations in the neuro-hormonal control of the pituitary could also be involved in pituitary tumors formation. The finding that most pituitary adenomas are monoclonal has stimulated a search for somatic mutations. For instance, activating mutations of the Gs protein, leading to constitutive stimulation of the cAMP pathway, have been found in a subset of GH-secreting adenomas. But GHRH (growth hormone-releasing hormone) tumoral hypersecretion also stimulates the cAMP pathway and causes acromegaly. Pituitary tumor formation might result from accumulation of several alterations that would determine the tumoral phenotype. The majority of these alterations remains to be found.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app