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Whipple's disease confined to the central nervous system

B De Coene, C Gilliard, P Indekeu, T Duprez, J P Trigaux
Neuroradiology 1996, 38 (4): 325-7
We report a 49-year-old woman with a left parietal lesion, shown on CT and MRI as an isolated ring-enhancing mass. The diagnosis of cerebral Whipple's disease was made by brain biopsy; there were no gastrointestinal symptoms nor periodic-acid Schiff-positive inclusions in the jejunal mucosa. This case illustrates atypical Whipple's disease, confined exclusively to the central nervous system.

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