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JOURNAL ARTICLE

REVIEW

Treatment of sepsis and septic shock: a review

W H Wiessner, L C Casey, J P Zbilut

Heart & Lung: the Journal of Critical Care 1995, 24 (5): 380-92; quiz 392-3

Septic shock is one of the leading causes of death in intensive care units, and its incidence is increasing. Mortality rates as high as 95% are reported, with rates of 60% or more even when diagnosed and treated promptly. This review examines the definition of septic shock, its pathogenesis, and supportive therapy, with particular attention to intervention during the septic shock cascade.

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