JOURNAL ARTICLE
Add like
Add dislike
Add to saved papers

[Adamantinoma and osteofibrous dysplasia of the tibia].

PURPOSE OF THE STUDY: Fibrous dysplasia and adamantinoma of the long bones are two different entities encountered on the same part of the tibial shaft. The relationship between these two diseases seems to be established. We describe a case with some common, features arguing for a single pathology.

MATERIAL AND METHODS: A seven year old boy presented in 1974 with a destructive lesion involving the cortex of the tibial shaft. The patient subsequently presented several fractures, treated surgically and has been followed for nineteen and a half years. The first biopsy specimen in 1974 led to the diagnosis of ossifying fibroma or fibrous dysplasia. It was reviewed with immunohistochemical technics but no epithelial component could be found.

RESULTS AND DISCUSSION: These pathologic aspects led to the diagnosis of adamantinoma associated with osteofibrous dysplasia of the tibia. Twenty five such cases were found in the literature. Two theories are proposed: 1) these two diseases are independent and coexist on the same bone; 2) there is only one disease with different features that are either those of fibrous dysplasia or those of adamantinoma. Immunohistochemical technics are needed for diagnosis.

CONCLUSION: Two sorts of adamantinoma can be observed on the long bones: adamantinoma without features of fibrous dysplasia with poor prognosis, adamantinoma with fibrous dysplasia's features called "differentiated adamantinoma" with a better prognosis.

Full text links

For the best experience, use the Read mobile app

Group 7SearchHeart failure treatmentPapersTopicsCollectionsEffects of Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Patients With Heart Failure Importance: Only 1 class of glucose-lowering agents-sodium-glucose cotransporter 2 (SGLT2) inhibitors-has been reported to decrease the risk of cardiovascular events primarily by reducingSeptember 1, 2017: JAMA CardiologyAssociations of albuminuria in patients with chronic heart failure: findings in the ALiskiren Observation of heart Failure Treatment study.CONCLUSIONS: Increased UACR is common in patients with heart failure, including non-diabetics. Urinary albumin creatininineJul, 2011: European Journal of Heart FailureRandomized Controlled TrialEffects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.Review

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

Read by QxMD is copyright © 2021 QxMD Software Inc. All rights reserved. By using this service, you agree to our terms of use and privacy policy.

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app