Suppression of brainstem reflexes in barbiturate coma

P J Grattan-Smith, W Butt
Archives of Disease in Childhood 1993, 69 (1): 151-2
Brainstem reflexes were examined in 23 children treated with thiopentone infusion and correlated with serum thiopentone concentrations. The results suggest that if all brainstem reflexes are lost with a serum thiopentone concentration less than 40 mg/l, it is unlikely to be due to the thiopentone alone. Other causes including brain death need to be considered.

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