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Tinea capitis: itraconazole in Trichophyton tonsurans infection.

BACKGROUND: Although griseofulvin is considered the standard treatment of tinea capitis, alternatives are being investigated in hopes of identifying more rapid and better cure rates.

OBJECTIVE: Our purpose was to determine the efficacy of itraconazole as therapy for tinea capitis.

METHODS: An open label study was performed on three patients who did not respond to or could not tolerate griseofulvin therapy.

RESULTS: A 30-day course of 100 mg of itraconazole daily resulted in clinical and mycologic cure in all three patients; no side effects were reported.

CONCLUSION: Although these results need to be confirmed by larger, controlled trials, it appears that itraconazole offers a viable alternative to griseofulvin for the treatment of children with tinea capitis.

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