We have located links that may give you full text access.
Trauma and multiple sclerosis.
Annals of Neurology 1994
The belief that trauma may precede or exacerbate multiple sclerosis (MS) has come primarily from anecdotal reports and case series that provide no rates and no basis for critical comparison. Each year in the United States, approximately 10,000 persons develop MS. A high proportion of the estimated 250,000 prevalence cases have one or more exacerbations, whereas one-third (or 83,000,000 persons in the United States) suffer a memorable injury; therefore, when trauma precedes MS onset or exacerbation, coincidence, as well as causal association, must be considered. For many patients, MS disability may have precipitated an injury, rather than follow one. Two major prospective cohort studies of MS indicate that physical trauma is not responsible for onset or exacerbation. A prospective cohort of patients with MS followed for eight years at the University of Arizona has failed to demonstrate an association between physical trauma and exacerbation. At the Mayo Clinic, cohorts identified in the Olmsted County, Minnesota population with MS, head injury (819), and lumbar disk surgery (942) demonstrated no correlation between onset or exacerbation of MS. Thus, on the basis of credible epidemiological studies, and particularly the studies of cohorts with MS and with trauma, there is no indication that either onset or exacerbation of MS is the result of physical trauma.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app