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Pulmonary venoocclusive disease in a patient with systemic lupus erythematosus.

Y Kishida, Y Kanai, S Kuramochi, Y Hosoda
Journal of Rheumatology 1993 December
A 26-year-old woman with systemic lupus erythematosus (SLE) developed dyspnea and hypoxemia on exertion. She died from rapidly progressive respiratory failure. Autopsy revealed right ventricular hypertrophy and occlusion of the pulmonary veins compatible with pulmonary venoocclusive disease (PVOD). Although PVOD has been reported in patients with suspected collagen vascular disease, this appears to be the first reported case of PVOD occurring in a patient with SLE.

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