Colour Doppler sonography: a new investigative modality for intraocular space-occupying lesions.

We report our experience with colour Doppler sonography (CDS) in 20 normal subjects and 25 patients with intraocular space-occupying lesions. The technique provided an in vivo cross-section of the vascular topography of space-occupying lesions in real time. Colour coding and spectral analysis helped to determine the direction and pattern of blood flow. CDS was found to be a useful diagnostic adjuvant, a guide to the treatment protocol, and helped in monitoring the progress of the disease. In conditions of the eye where unclear media hindered a clinical evaluation, CDS sonography was a safe, easily reproducible and non-invasive investigative tool. With further technical advances in waveform analysis and quantitative assessment, CDS holds promise as an investigative modality of choice in the future.