Deficient metanephric blastema—a cause of oligomeganephronia?

S V Foster, E P Hawkins
Pediatric Pathology 1994, 14 (6): 935-43
The histopathology and morphometric findings in two cases of oligomeganephronia occurring in a fetus and a preterm infant are reported. Metanephric blastema was decreased in the kidney from an 18-week fetus and was absent in the kidney from a liveborn preterm infant of 33 weeks gestation. These findings support the hypothesis that a primary deficiency of metanephric blastema may be a pathogenetic mechanism of oligomeganephronia.

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