We have located links that may give you full text access.
ENGLISH ABSTRACT
JOURNAL ARTICLE
[Pediatric surveillance of invasive infections caused by Haemophilus influenzae type b in children in the period following introduction of vaccination].
Nederlands Tijdschrift Voor Geneeskunde 1995 April 30
OBJECTIVE: Evaluation of the effect of vaccination against Haemophilus influenzae type b (Hib) on the occurrence of invasive Hib infections in children since its introduction into the national immunization programme in April 1993.
DESIGN: Observational study.
SETTING: Nationwide investigation.
METHOD: Data collected through active surveillance of invasive Hib infections by paediatricians for the period from October 1993 to September 1994 (11 months) were compared with data from the meningitis surveillance by the Netherlands Reference Laboratory for Bacterial Meningitis.
RESULTS: A total of 139 paediatric reports of invasive disease by H. influenzae concerned 57 cases of only meningitis, 35 of meningitis with sepsis, 2 of meningitis with arthritis, one of meningitis with arthritis and osteomyelitis, 34 of epiglottitis including one case with sepsis, 8 of only sepsis and 2 of only arthritis. All proven infections by Hib occurred in children who had not or incompletely been vaccinated. One child with sepsis had had three vaccinations and became ill five months later; the isolated bacterial strain was not serotyped. Typing was performed in only 80% of the isolates, of which 98% were of type b. Appropriate culturing and typing was often omitted in case of epiglottitis.
CONCLUSION: The effect of vaccination against Hib became apparent in a small number of cases of invasive Hib disease reported by paediatricians; the peak incidence of meningitis no longer occurred in children under one year of age but in children aged one year. The paediatric surveillance described offers possibilities for monitoring Hib epidemiology.
DESIGN: Observational study.
SETTING: Nationwide investigation.
METHOD: Data collected through active surveillance of invasive Hib infections by paediatricians for the period from October 1993 to September 1994 (11 months) were compared with data from the meningitis surveillance by the Netherlands Reference Laboratory for Bacterial Meningitis.
RESULTS: A total of 139 paediatric reports of invasive disease by H. influenzae concerned 57 cases of only meningitis, 35 of meningitis with sepsis, 2 of meningitis with arthritis, one of meningitis with arthritis and osteomyelitis, 34 of epiglottitis including one case with sepsis, 8 of only sepsis and 2 of only arthritis. All proven infections by Hib occurred in children who had not or incompletely been vaccinated. One child with sepsis had had three vaccinations and became ill five months later; the isolated bacterial strain was not serotyped. Typing was performed in only 80% of the isolates, of which 98% were of type b. Appropriate culturing and typing was often omitted in case of epiglottitis.
CONCLUSION: The effect of vaccination against Hib became apparent in a small number of cases of invasive Hib disease reported by paediatricians; the peak incidence of meningitis no longer occurred in children under one year of age but in children aged one year. The paediatric surveillance described offers possibilities for monitoring Hib epidemiology.
Full text links
Trending Papers
Monitoring Macro- and Microcirculation in the Critically Ill: A Narrative Review.Avicenna Journal of Medicine 2023 July
Euglycemic Ketoacidosis in Two Patients Without Diabetes After Introduction of Sodium-Glucose Cotransporter 2 Inhibitor for Heart Failure With Reduced Ejection Fraction.Diabetes Care 2023 November 22
ASA Consensus-based Guidance on Preoperative Management of Patients on Glucagon-like Peptide-1 Receptor Agonists.Anesthesiology 2023 November 21
Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials.Annals of Emergency Medicine 2023 November 22
Association between postinduction hypotension and postoperative mortality: a single-centre retrospective cohort study.Canadian Journal of Anaesthesia 2023 November 22
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
Read by QxMD is copyright © 2021 QxMD Software Inc. All rights reserved. By using this service, you agree to our terms of use and privacy policy.
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app