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Neutrophilic eccrine hidradenitis: report of two cases.

H Kanzaki, T Oono, E Makino, J Arata, M Oda, A Akazai
Journal of Dermatology 1995 Februrary
BACKGROUND: Neutrophilic eccrine hidradenitis (NEH) is an uncommon, self-limited dermatosis usually attributed to anti-cancer chemotherapy. It is characterized histologically by necrosis of the eccrine gland and neutrophilic infiltrate.

OBSERVATIONS: We saw NEH in a 5-year-old boy with acute lymphoblastic leukemia and a 4-year-old girl with acute monocytic leukemia. NEH developed after the anti-leukemic chemotherapy including high dose cytarabine. The eruption was composed of vesicles, papules, and plaques.

CONCLUSIONS: Histological findings were compatible with those described in the literature. NEH in our two patients could be attributed to high doses of cytarabine.

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