RESEARCH SUPPORT, U.S. GOV'T, P.H.S.
The treatment of mitochondrial myopathies and encephalomyopathies.
Biochimica et Biophysica Acta 1995 May 25
This paper briefly summarizes the results of a long-term, open pharmacotherapy trial in 16 patients with well-characterized mitochondrial disease. Outcome measures included repeated clinical evaluation, 31P-NMR spectroscopy and near-infrared spectroscopy. Treated patients appeared to survive longer with less functional disability and medical complications than typically seen in clinical practice.
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