JOURNAL ARTICLE
RESEARCH SUPPORT, U.S. GOV'T, P.H.S.
REVIEW
Add like
Add dislike
Add to saved papers

Sepsis and multiple organ dysfunction syndrome: a clinical-mechanistic overview.

Multiple organ dysfunction syndrome (MODS) is the primary cause of death in patients admitted to ICUs. Despite the development of better resuscitation, more powerful antibiotics, and more sophisticated methods for organ support, our ability to rescue patients from established MODS has not improved significantly since the syndrome was first described two decades ago. Rapid advancements in molecular biology have begun to unravel some of the potential mechanisms behind the development of this syndrome, and have suggested many potential therapeutic approaches. To effectively use these new treatment options as they become available, it is necessary to have a clear understanding of how these therapies fit into the current theories on the pathophysiology of MODS. Thus, the goal of this article is to integrate what is new in our understanding of the development of MODS with current concepts regarding potential therapies of this complex and perplexing syndrome.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app