We have located links that may give you full text access.
ENGLISH ABSTRACT
JOURNAL ARTICLE
[Invention of a forced-air-ventilated micro-isolation cage and rack system--environment within cages: temperature and ammonia concentration].
Experimental Animals 1995 October
There is little information about microenvironments within laboratory animal cages, although several guidelines on the macroenvironment in laboratory animal rooms have been reported. We have developed a forced-air ventilation system (FVMIS) to improve laboratory animal well-being. In this study, we tested the performance of the FVMIS in terms of temperature and ammonia concentration within cages. Continuous measurement of temperature and ammonia concentration was carried out in FVMIS cages housing 5 rats each. The average temperature within the cages was 22 degrees C to 24 degrees C, and the temperature difference among cages was 0.93 degrees C. The air exchange rate used was 65 changes per hour. FVMIS was capable of controlling the temperature within cages uniformly and accurately with a lower air exchange rate than with the conventional system. The ammonia concentration reached 20 ppm within 9 days in a filtercapped conventional cage, but took 13 to 16 days to reach 20 ppm with FVMIS. It appears that FVMIS is capable of suppressing the ammonia concentration increase in cages, thereby reducing the frequency of cage changes and the stress to laboratory animals when cages are changed. In the present study, it was confirmed that FVMIS contributes not only to microenvironmental control in terms of temperature and ammonia concentration with a lower air exchange rate, but also to animal well-being.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app