JOURNAL ARTICLE

Histochemical and ultrastructural aspects of m. vastus lateralis in sedentary old people (age 65—89 years)

R Scelsi, C Marchetti, P Poggi
Acta Neuropathologica 1980, 51 (2): 99-105
7435151
Biopsies for histochemical and ultrastructural studies were taken from the M. vastus lateralis of 45 healthy sedentary men and women aged 65--89 years. With increasing age the histochemical reactions reveal changes inthe fibre type distribution characterized by a decrease in the percentage and predominant atrophy of type II fibres. The most frequent changes in the oldest subjects are: targetoid fibres, type I fibre predominance, and type grouping phenomena; expressions of denervation. Myopathic alterations are observed unusually. Electron microscopic findings are characterized by myofibrillar disorder, streaming of Z line and rod formation, and dilatation and increase of sarcoplasmic reticulum. As the age increases, the fibres become richer in intracellular lipid droplets and lysosomes. Intramuscular microcirculatory alterations, consisting of arteriolosclerotic changes and increase in width of the capillary basement membrane, are also observed and discussed.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Trending Papers

Remove bar
Read by QxMD icon Read
7435151
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.