We have located links that may give you full text access.
Coronary intimal necrosis occurring as an early stage of atherosclerotic involvement.
Atherosclerosis 1981 July
In a population sample in whom violent accident was the cause of death, the following prevalence of coronary intimal necrosis, occurring as an independent lesion and as an early step of atherosclerotic involvement, was revealed: 2% of children 6--10 years old, 6% of children and juveniles 11--15 years old, 14% of adolescents 16--20 years old, 32% of young adults 21--25 years old, 56% of young adults 26--30 years old, 72% of mature adults 31--35 years old and 84% of mature adults 36--40 years old. In each age subgroup, the percentage of subjects with coronary intimal necrosis was greater than the percentage of subjects with coronary atherosclerotic plaques. A centrifugal extension with age of intimal necrosis, along the coronary tree in the direction of blood flow, was observed. Histologically, the coronary intimal necrosis exhibited a mucoid form, a swelling form and a dissecting form. Indirect evidence was offered that some areas of coronary intimal necrosis formed an adequate nidus for lipid and fibrin accumulation and also induced the development of a peculiar type of subendothelial connective tissue. These successive changes led to the onset of atheroma-like lesions with a prevalence of lipid deposits, or of intramural thrombi or of a fibro-hyaline cap. The onset, extent and evolution of coronary intimal necrosis was accelerated by the male sex, by some minor deviations from the basal branching anatomical pattern of the coronary arteries, by the main risk factors for coronary heart disease, as well as by some terminal diseases, such as the generalized form of sarcoidosis and the renal complications of systemic lupus erythematosus.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app