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Familial occurrence of meconium ileus

J L Allan, M Robbie, P D Phelan, D M Danks
European Journal of Pediatrics 1981, 135 (3): 291-2
A recurrence rate for meconium ileus of 39% was found among C.F. affected siblings in a study of 488 families with at least one C.F. child born over a 24 year period. The recurrence rate was highly significant and indicated a familial trend for the occurrence of meconium ileus. The findings of the study support the existence of genetic heterogeneity in cystic fibrosis.

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