[Acute coagulation disorder following amniotic fluid infusion]

A Schrempel, E Fiebing
Zentralblatt Für Gynäkologie 1982, 104 (23): 1545-51
Penetration of amniotic fluid and its components into maternal circulation may cause more or less sizable obstruction of terminal sections of pulmonary circulation. Disseminated intravascular coagulation (DIC) will be the result of thromboplastic activity in amniotic fluid. Excessive fibrinolytic activity is likely to develop as counterregulation and to cause severe impairment of coagulation. The principle which governs the pathogenesis of such acutely acquired impairment of coagulation is discussed together with necessary diagnosis and therapy, with reference being made to two cases of differentiated courses.

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