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[Alkaptonuria (ochronosis)].

K Guggenberger, O Seidl, C Schmoeckel
Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete 1983 July
A 39-year-old male patient observed an increasing bluish pigmentation of the ear cartilage associated with recurrent back-pain. Darkening of the urine after the addition of sodium hydroxide led to the suspected diagnosis of alkaptonuria. This diagnosis was confirmed by the detection of urinary homogentisic acid by thin-layer chromatography.

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