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Penicillin concentrations in blood and spinal fluid after a single intramuscular injection of penicillin G benzathine.

G Frentz, P B Nielsen, F Espersen, A Czartoryski, H Aastrup
European Journal of Clinical Microbiology 1984 April
The concentration of penicillin in cerebrospinal fluid and blood was measured after a single i.m. injection of 1.44 g penicillin G benzathine in 18 individuals (4 with neurosyphilis and 14 with neurological symptoms but not syphilis). Only one person had a treponemicidal concentration in the cerebrospinal fluid.

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