Investigating the adenocarcinoma of unknown origin (ACUP): a cost benefit analysis

M N Maisey, S V Ellam
Revue D'épidémiologie et de Santé Publique 1984, 32 (1): 57-61
This paper attempts to assess three approaches to the investigation of a patient with histological metastatic adenocarcinoma when the primary tumour of origin is not clear on the initial presentation. These different approaches are evaluated semi-quantitatively. Estimated costs and morbidity of investigations and treatment, increased survival, and improvement in quality of life are taken into account in this analysis. A sample schema of investigation which will maximise the potential benefit as well as minimise the cost to the health service resources and the human cost to the patient is proposed.

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