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Malignant melanoma brain metastases. Review of Roswell Park Memorial Institute experience

S Madajewicz, C Karakousis, C R West, J Caracandas, A M Avellanosa
Cancer 1984 June 1, 53 (11): 2550-2
One-hundred twenty five of 700 patients with malignant melanoma treated at Roswell Park Memorial Institute from 1972 to 1978 were found to have brain metastases. Seventy-three percent of the patients had multiple brain metastases. Male to female ratio was 1.9:1. The median survival of the untreated group of patients was 3 weeks as compared with that of 6 weeks for the patients maintained on steroids only, 9 weeks for those who received radiotherapy, 11 weeks for the patients treated with intraarterial chemotherapy, and 26 weeks for the patients who underwent successful surgical excision of a solitary lesion.

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