JOURNAL ARTICLE

Apnea documentation for determination of brain death in children

T W Rowland, J H Donnelly, A H Jackson
Pediatrics 1984, 74 (4): 505-8
6435086
Discontinuing ventilatory support for determination of respiratory drive is a recognized means of assessing clinical brain death. Methodology must include a means for assuring adequate oxygenation during the test as well as providing sufficient duration for appropriate hypercarbia. Nine patients with other findings of clinical brain death were prospectively assessed with a standardized apnea test protocol. None demonstrated spontaneous respirations. Whereas adequate oxygenation was maintained in each case, wide variability was evident in degree of hypercarbia and acidosis.

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