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Detection of human papillomavirus DNA sequences in conjunctival papilloma.

J H Lass, A S Grove, J J Papale, D M Albert, A B Jenson, W D Lancaster
American Journal of Ophthalmology 1983 November
Two histologically proven conjunctival papillomas (one from a 33-month-old boy and the other from a 28-year-old woman) were examined for the presence of papillomavirus by DNA molecular hybridization. The first case, a recurrent tumor known to be positive for papillomavirus structural antigen, demonstrated human papillomavirus DNA sequences that cross-hybridized to a human papillomavirus type 11 DNA probe. The second case, an initial tumor, which was negative for papillomavirus structural antigen, demonstrated no viral DNA sequences by hybridization.

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