Erythema multiforme-like papules after COVID vaccine administration.

Theodore J Daly, Gregory T Smith, Steve A McClain

Dermatology Online Journal 2024 June 15

A unique dermatopathology incident arose after administration of the mRNA-1273 SARS-CoV-2 (Moderna) vaccine. Specifically, a transient purpuric interface dermatitis occurred 5 days post-second vaccine with the presentation of erythematous papules with erythema multiforme-type findings. A patient developed purpuric interface dermatitis with micro-vesiculation post-vaccination which ultimately resolved without sequelae.

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