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A three-way organelle junction controls PI(4)P metabolism and mitochondrial division.

York Posor, Volker Haucke
Journal of Cell Biology 2024 September 2
Membrane contact sites (MCS) facilitate communication between organelles. Casler et al. (https://doi.org/10.1083/jcb.202308144) show that tripartite MCS between mitochondria, the endoplasmic reticulum (ER), and the plasma membrane (PM) regulate mitochondrial division and the distribution of phosphatidylinositol 4-phosphate [PI(4)P] on the PM.

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