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Susceptibility and HLA-B27 in post-dysenteric arthropathies.

C G van Bohemen, R J Lionarons, P van Bodegom, H J Dinant, J E Landheer, A J Nabbe, F C Grumet, H C Zanen
Immunology 1985 October
A recent outbreak of bacillary dysentery in The Netherlands revealed that, despite the close association of HLA-B27 with post-dysenteric or reactive arthritis (ReA), not even in one family did all HLA-B27 positive patients infected by an arthritogenic bacterium, develop ReA. This dissociation shows that additional factors beside B27 may determine susceptibility to ReA.

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