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7-Dehydrocholesterol: A sterol shield against an iron sword.

Molecular Cell 2024 April 5
Li et al. and Freitas et al. recently identified 7-dehydrocholesterol (7-DHC), a sterol produced through the cholesterol biosynthetic pathway, as a lipid-soluble antioxidant that protects cells from ferroptosis, a cell death pathway triggered by iron-catalyzed phospholipid peroxidation.1 , 2 .

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