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The links are still missing: Revisiting the role of RNA as a guide for chromatin-associated proteins.

Molecular Cell 2024 April 5
A new study in Molecular Cell by Guo et al.1 and two studies in Cell Reports by Healy et al.2 and by Hall Hickman and Jenner3 show how PRC2 and other chromatin regulators do not appear to bind RNA in vivo, challenging the importance of RNA for their function.

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