Grand Rounds Review Article: "Allergen immunotherapy for asthma".

Allergen immunotherapy (AIT) is a disease modifying treatment for IgE mediated allergies reducing disease burden and symptoms in patients with allergic rhinitis, with or without asthma. The growing evidence that AIT also has the potential to facilitate achieving asthma control in patients with allergic asthma resulted in its acknowledgement by international bodies (GINA and EAACI) as add-on treatment for mild/moderate asthma. Although there have been promising developments in biomarkers for patient selection and for AIT efficacy evaluation in asthma patients, a lot more data are still required.