Prevalence of SARS-CoV-2 Viremia in Presymptomatic Blood Donors in the Delta and Omicron Variant Eras.
Paula Saá, Rebecca V Fink, Hina Dawar, Clara Di Germanio, Leilani Montalvo, David J Wright, David E Krysztof, Steven H Kleinman, Theresa Nester, Debra A Kessler, Rebecca L Townsend, Bryan R Spencer, Hany Kamel, Jackie Vannoy, Michael P Busch, Susan L Stramer, Mars Stone, Philip J Norris
Presymptomatic plasma samples from 1596 donors reporting coronavirus disease 2019 infection or symptoms after blood donation were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and anti-S and anti-N antibodies. Prior infection and vaccination both protected from developing SARS-CoV-2 RNAemia and from symptomatic infection. RNAemia rates did not differ in the Delta and Omicron variant eras.