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Fewer worsening heart failure events with HeartLogic TM on top of standard of care: a propensity-matched cohort analysis.
Journal of Cardiac Failure 2023 May 22
BACKGROUND: The implantable cardiac defibrillator (ICD) based HeartLogicTM algorithm aims to detect impending fluid retention in heart failure (HF) patients. Studies show that HeartLogicTM is safe to integrate in clinical practice. The current study investigates if HeartLogicTM provides clinical benefit on top of standard care and device telemonitoring in HF patients.
METHODS: A multicenter retrospective propensity-matched cohort analysis was performed in HF patients with and ICD and compared HeartLogicTM to conventional telemonitoring. Primary endpoint was the number of worsening HF events. HF hospitalizations and ambulatory HF visits were also evaluated.
RESULTS: Propensity score matching yielded 127 pairs (median age 68 years, 80% male). Worsening HF events occurred more frequently in the control group (2, IQR 0-4) compared to the HeartLogicTM group (1, IQR 0-3, p=0.004). The number of HF hospitalization days was higher in controls compared to the HeartLogicTM group (8, IQR 5-12 vs. 5, IQR 2-7, p=0.023) and ambulatory visits for diuretic escalation were more frequent in the control group than in the HeartLogicTM group (2, IQR 0-3 vs. 1, IQR 0-2, p=0.0001).
CONCLUSION: Integrating the HeartLogicTM algorithm in a well-equipped HF care path on top of standard care, is associated with fewer worsening HF events and shorter duration of fluid retention related hospitalizations.
METHODS: A multicenter retrospective propensity-matched cohort analysis was performed in HF patients with and ICD and compared HeartLogicTM to conventional telemonitoring. Primary endpoint was the number of worsening HF events. HF hospitalizations and ambulatory HF visits were also evaluated.
RESULTS: Propensity score matching yielded 127 pairs (median age 68 years, 80% male). Worsening HF events occurred more frequently in the control group (2, IQR 0-4) compared to the HeartLogicTM group (1, IQR 0-3, p=0.004). The number of HF hospitalization days was higher in controls compared to the HeartLogicTM group (8, IQR 5-12 vs. 5, IQR 2-7, p=0.023) and ambulatory visits for diuretic escalation were more frequent in the control group than in the HeartLogicTM group (2, IQR 0-3 vs. 1, IQR 0-2, p=0.0001).
CONCLUSION: Integrating the HeartLogicTM algorithm in a well-equipped HF care path on top of standard care, is associated with fewer worsening HF events and shorter duration of fluid retention related hospitalizations.
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