Fetal risk of anesthesia and surgery during pregnancy

P G Duncan, W D Pope, M M Cohen, N Greer
Anesthesiology 1986, 64 (6): 790-4
In an attempt to define the risk to the fetus associated with anesthesia and surgery during pregnancy, a study was performed using health insurance data from the province of Manitoba (1971 to 1978). Each of the 2,565 women undergoing incidental surgery during pregnancy (Group A) was paired with a pregnant female not undergoing surgery (Group B) by maternal age and area of residence. Both groups were linked to a separately maintained provincial congenital-anomalies registry to ascertain the frequency of anomalies. There was no significant difference in the rate of congenital anomalies between the two groups, implying no strong teratogenic effect. However, there was an increased risk of spontaneous abortion in those undergoing surgery with general anesthesia in the first or second trimester, most notably after gynecologic procedures (estimated risk ratio = 2.00), but also following procedures anatomically remote from the conceptus (estimated risk ratio = 1.54). While it is concluded that surgery with general anesthesia is associated with a higher incidence of abortion, it is conjectural at present which factor(s) account for the observed increase in fetal risk.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.