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Primary cutaneous lymphomas: Exploration of 10-year data at a supra-regional MDT in Glasgow, UK.
Clinical and Experimental Dermatology 2023 May 5
Primary cutaneous lymphomas (PCL) are non-Hodgkin lymphomas, presenting in the skin. They are classified into cutaneous B-cell (CBCL), or cutaneous T-cell lymphomas (CTCL), the latter being the most common. The most common CTCL subtypes are mycosis fungoides (MF) and Sézary syndrome (SS).1 All cases should be discussed at a specialist multidisciplinary team (MDT) meeting.2 This report is the first published review of PCL MDT case discussion in the UK. Cases from the supra-regional specialist cutaneous lymphoma MDT in Glasgow, between 2008 and 2019, were reviewed. Our objectives were: assess frequency of PCL subtype; review documentation of CTCL staging; review management of MF/SS. Of 356 cases, 103 (29%) were CBCL. The majority (n=200, 56%) were CTCL. MF/SS was the final diagnosis in 120 (34%). Staging was documented in 44% (n=53) MF/SS cases. Management largely followed guidelines, topical corticosteroids (TCS) were the most common treatment (n=93, 87%) (Figure 1).2 Frequency of PCL subtype is largely comparable to previously published data (Table 1). Documentation of CTCL staging is low, but higher than other reports.3 Our work begins to address the gap in real-world data on CTCL. Going forward, a standardised approach to data collection would inform clinical practice.
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