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Does obesity predict morbidity and mortality amongst patients undergoing transfemoral amputations?

Vascular 2023 March 21
BACKGROUND: We investigated the role of obesity on morbidity and mortality in patients undergoing above knee amputation.

METHODS: Data of 4225 patients undergoing AKAs was extracted from NIS Database (2016-2019) for a retrospectively matched case-control study and were grouped into; Non-obese (N-Ob-BMI <29.9 kg/m2 ; n = 1413), class I/II obese (Ob-I/II-BMI: 30-39.9 kg/m2 ; n = 1413), and class III obese groups (Ob-IIIBMI > 40; n = 1399). Morbidity, mortality, length of stay, and hospital charges were analyzed.

RESULTS: Blood loss anemia (OR = 1.42; 95% CI = 1.19-1.64), superficial SSI (OR = 5.10; 95% CI = 1.4717.63) and acute kidney injury (AKI- OR = 1.42; 95% CI = 1.21-1.67) were higher in Ob-III patients. Mortality was 5.8%, 4.5%, and 6.4% in N-Ob, Ob-I/II and Ob-III patients ( p < 0.001; Ob-I/II vs. Ob-III), respectively. Hospital LOS was 3 days higher in Ob-III (16.1 ± 18.0), comparatively resulting in $25,481 higher inpatient-hospital charge.

CONCLUSION: Patients in Ob-III group were noted to have increased morbidity, higher LOS, and inpatient-hospital cost.

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