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Beauty and death of motion.

Translational research aims to apply what we learn in the lab to the patient's care in the clinical setting. Animal studies for Parkinson's disease and Deep Brain Stimulation (DBS) are particularly intriguing topics that show the value of translational research. Training a monkey to complete a task, inducing Parkinsonian symptoms, and comparing kinematic differences with various DBS settings is a transformative process of motion creation, death, and rebirth. The historical context of the drug used to induce Parkinsonian symptoms and DBS technology demonstrates how our field progresses from trial and error and evolves into enhancing patient care. We can use the same methods from animal studies to verify outcomes during a patient's DBS surgery. The narrative of one monkey demonstrates the concepts of translational research, research ethics, and medical history.

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Group 7SearchHeart failure treatmentPapersTopicsCollectionsEffects of Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Patients With Heart Failure Importance: Only 1 class of glucose-lowering agents-sodium-glucose cotransporter 2 (SGLT2) inhibitors-has been reported to decrease the risk of cardiovascular events primarily by reducingSeptember 1, 2017: JAMA CardiologyAssociations of albuminuria in patients with chronic heart failure: findings in the ALiskiren Observation of heart Failure Treatment study.CONCLUSIONS: Increased UACR is common in patients with heart failure, including non-diabetics. Urinary albumin creatininineJul, 2011: European Journal of Heart FailureRandomized Controlled TrialEffects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.Review

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