We have located links that may give you full text access.
Different calcification patterns of tricuspid and bicuspid aortic valves and their clinical impact.
Interactive Cardiovascular and Thoracic Surgery 2022 November 16
OBJECTIVES: Mechanical strain plays a major role in the development of aortic calcification. We hypothesized that (a) valvular calcifications are most pronounced at the localizations subjected to the highest mechanical strain and (b) calcification patterns are different in patients with bicuspid and tricuspid aortic valves.
METHODS: Multi slice computed tomography scans of 101 patients with severe aortic stenosis were analyzed using a 3D-post processing software to quantify calcification of tricuspid aortic valves (n = 51) and bicuspid aortic valves (n = 50) after matching.
RESULTS: BAV exhibited higher calcification volumes and increased calcification of the non-coronary cusp with significantly higher calcification of the free leaflet edge. The non-coronary cusp showed the highest calcium load compared to the other leaflets. Patients with annular calcification above the median had an impaired survival compared to patients with low annular calcification, whereas calcification of the free leaflet edge above the median did not (p = 0.53).
CONCLUSION: Calcification patterns are different in aortic stenosis patients with bicuspid and tricuspid aortic valves. Patients with high annular calcification might have an impaired prognosis.
METHODS: Multi slice computed tomography scans of 101 patients with severe aortic stenosis were analyzed using a 3D-post processing software to quantify calcification of tricuspid aortic valves (n = 51) and bicuspid aortic valves (n = 50) after matching.
RESULTS: BAV exhibited higher calcification volumes and increased calcification of the non-coronary cusp with significantly higher calcification of the free leaflet edge. The non-coronary cusp showed the highest calcium load compared to the other leaflets. Patients with annular calcification above the median had an impaired survival compared to patients with low annular calcification, whereas calcification of the free leaflet edge above the median did not (p = 0.53).
CONCLUSION: Calcification patterns are different in aortic stenosis patients with bicuspid and tricuspid aortic valves. Patients with high annular calcification might have an impaired prognosis.
Full text links
Related Resources
Trending Papers
Diastolic Dysfunction and Renal Disease: Analysis, Mechanisms, and Different Perspectives.Curēus 2025 January
Combination therapy: an upcoming paradigm to improve kidney and cardiovascular outcomes in chronic kidney disease.Nephrology, Dialysis, Transplantation 2025 Februrary 5
EULAR recommendations for the treatment of systemic sclerosis: 2023 update.Annals of the Rheumatic Diseases 2025 January
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2025 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app