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Omicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections.

Rune M Pedersen, Line L Bang, Ditte S Tornby, Lone W Madsen, Dorte K Holm, Thomas V Sydenham, Isik S Johansen, Thøger G Jensen, Ulrik S Justesen, Thomas E Andersen
Emerging Infectious Diseases 2022 November 9
Worldwide, millions of persons have received multiple COVID-19 vaccinations and subsequently recovered from SARS-CoV-2 Omicron breakthrough infections. In 2 small, matched cohorts (n = 12, n = 24) in Denmark, we found Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provided improved Omicron BA.5 neutralization over 3-dose vaccination alone.

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