Rhabdomyosarcomatous component in dedifferentiated chondrosarcoma

A Niezabitowski, G Edel, A Roessner, E Grundmann, C Timm, P Wuisman
Pathology, Research and Practice 1987, 182 (2): 275-82
The case of a 57-year-old male is described with an extended bone tumor in the proximal left femur. The tumor is histologically classified as dedifferentiated chondrosarcoma. Immunohistologic examination revealed a strong positive reaction for desmin mainly in the tumor giant cells in the dedifferentiated areas, whereas chondroblasts in the low grade chondrosarcoma areas reacted negatively with desmin. In accordance with some cross striation in polymorphic tumor cells this points to a rhabdomyosarcomatous component in the dedifferentiated portions of the tumors. Thus, in addition to fibrosarcomatous, osteosarcomatous and malignant fibrous histiocytoma-like areas, our case presents another sarcomatous constituent in dedifferentiated chondrosarcoma.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"