The Transaxillary Route as a Second Access Option in TAVI Procedures: Experience of a Single Centre.

Background: The aim of our study was to determine the feasibility and efficacy of transaxillary (TAX) TAVI in patients not eligible for the transfemoral route. Methods: This is a retrospective study of a single center. We analysed 262 patients treated with TAVI. In 17 patients (6.5%), the procedure was performed with the TAX approach. Procedural and hospital data, 30-day safety, and clinical efficacy were assessed and compared between the transfemoral and TAX groups. Results: In the TAX groups, we found a higher prevalence of men ( p = 0.001), smokers ( p = 0.033), and previous strokes ( p = 0.02). The EUROSCORE II was higher in the TAX group ( p = 0.014). The success rate of the device was 100%. TAX was associated with a longer procedure time ( p = 0.001) and shorter median device time ( p = 0.034) in minutes. Patients treated with TAX had a longer hospital stay ( p = 0.005) and higher overall bleeding rate ( p = 0.001). Peripheral neurological complications were more frequent with TAX ( p = 0.001), which almost completely resolved by 30 days. Conclusions: TAX TAVI is safe and effective and should be considered as a second choice when transfemoral TAVI is not feasible due to severe comorbidities.