RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
Hijacking of host mitochondria by Toxoplasma gondii and SARS-CoV-2.
Trends in Parasitology 2022 April
Mitochondria regulate energy production, cell cycle, and immune signaling. Li et al. recently reported that Toxoplasma gondii induces the shedding of mitochondrial outer membrane to promote its growth. Intriguingly, the hijacking of host mitochondria has been shown to play an essential role in the pathogenesis of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
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