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Extensively Drug-Resistant Typhoid Fever in the United States.

Michael J Hughes, Meseret G Birhane, Layne Dorough, Jared L Reynolds, Hayat Caidi, Kaitlin A Tagg, Caroline M Snyder, Alexander T Yu, Shana M Altman, Michelle M Boyle, Deepam Thomas, Amy E Robbins, HaeNa A Waechter, Irina Cody, Eric D Mintz, Bruce Gutelius, Gayle Langley, Louise K Francois Watkins
Open Forum Infectious Diseases 2021 December
Cases of extensively drug-resistant (XDR) typhoid fever have been reported in the United States among patients who did not travel internationally. Clinicians should consider if and where the patient traveled when selecting empiric treatment for typhoid fever. XDR typhoid fever should be treated with a carbapenem, azithromycin, or both.

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