18 F-FDG PET/CT imaging features of Cardiac Arrhythmia - induced by Panitumumab.

Panitumumab is a new humanized anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb) approved for the treatment of advanced colorectal cancer. There is an increase in the use of this drug due to a good response rate and possible secondary resection in advance colorectal cancer. Here we present 18 F-FDG PET/CT imaging findings of cardiac arrhythmia in a patient receiving Panitumumab for the treatment of metastatic infiltrating rectal adenocarcinoma. Cardiotoxicity is a known adverse effect associated with Panitumumab. By far to our knowledge, no documented imaging findings for the same are available in the literature.