We have located links that may give you full text access.
JOURNAL ARTICLE
REVIEW
The role of M 6 A modification in the regulation of tumor-related lncRNAs.
Molecular Therapy. Nucleic Acids 2021 June 5
N 6 -methyladenosine (m6 A) is the most abundant modification in eukaryotic cells, and it regulates RNA transcription, processing, splicing, degradation, and translation. Long non-coding RNAs (lncRNAs), as transcriptional products with no or limited protein coding ability more than 200 nt in length, play an important role in epigenetic modification, mRNA transcription, splicing, stability, translation, and other biological functions. Extensive studies have shown that both m6 A modification and lncRNAs are involved in the pathogenesis of various diseases, such as kinds of cancers, heart failure, Alzheimer's disease, periodontitis, human abdominal aortic aneurysm, and obesity. To date, m6 A modification has been identified as an important biological function in enrichment and regulation of lncRNAs. In this review, we summarize the role of m6 A modification in the regulation and function of tumor-related lncRNAs. Moreover, we discuss the potential applications and possible future directions in the field.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app